2 Mar

We are moving…

We want to share exciting news: the lab is moving to the University Hospital RWTH Aachen, joining the department of Transfusion Medicine and Cell Therapeutics headed by Prof. Hannes Klump. We are eager to leverage our expertise in RNA biology to foster translational and applied research in stem cell biology and hematopoiesis.

We want to thank all our colleagues at the University of Regensburg for their continuous support over the past 11 years. The Collaborative Research Center SFB960 and the close collaborations with our partners in Regensburg were instrumental for our research, allowing us to successfully address exciting questions in RNA biology.

29 Apr

Ribosome Profiling Course

We had an exciting time during the practical course on rapid and high sensitivity analyses of cellular translation by ribosome profiling. 13 international participants joined us in Regensburg for a five day lab course during which they very successfully prepared ribsome profiling libraries from a human cell line using only minute amounts of input material.

We would like to thank all participants for their enthusiasm and for sharing with us insight into their exciting research projects! We had a great time working together and discussion science with you.

We also thank Sebastian Leidel (Department of Chemistry, Biochemistry and Pharmaceutical Sciences, University of Bern, Switzerland) and Thomas Preiss (John Curtin School of Medical Research at the Australia National University, Australia) for supporting the course with exciting lectures and for contributing expert opinions and insight into the challenges and pitfalls of performing ribosome profiling experiments.

We are grateful for the support by the Graduate Research Academy RNA Biology of the Collaborative Research Center SFB 960 and siTOOLs Biotech.

21 Dec

Ribosome Profiling Practical Course

From January 17th to 21st, we will run a practical course on ribosome profiling at the Justus-Liebig-University in Gießen. Focusing on our newly-developed and high-sensitivity protocol, we will teach students of the DFG-funded Research Training Group 2355 ‘Regulatory networks in the mRNA life cycle: from coding to non-coding RNAs’ how to analyze cellular translation using ribosome profiling. We are very much looking forward to the course and to introducing our ultra-rapid protocol to our colleagues for the first time.

18 Oct

New publication from the lab: multi-omics to unravel stress-dependent gene expression changes

Together with our collaborator Robert Ahrends (at the Universität Wien), we published a summary of our recent work in the BIOspektrum journal. We describe how multi-omics approaches can yield novel and clinically relevant insights into stress-mediated gene expression changes. The article (in German) can be accessed here. The work has been a close collaboration within the BMBF-funded junior research consortium Systems Biology of the Unfolded Proteins Response in Glioma (SUPR-G).